Human olfactory detection of homologous n-alcohols measured via concentration–response functions
نویسندگان
چکیده
منابع مشابه
Human olfactory detection of homologous n-alcohols measured via concentration-response functions.
We explored in humans concentration-detection functions for the odor of the homologous n-alcohols ethanol, 1-butanol, 1-hexanol, and 1-octanol. These functions serve to establish structure-activity relationships, and reflect the pharmacology of the olfactory sense at the behavioral level. We tested groups of 14 to 17 subjects (half of them females), averaging 31 to 35 years old. An 8-station va...
متن کاملOlfactory Stimulation of Blowflies by Homologous Alcohols
The response of the blowfly Phormia regina to stimulation by alcohols in the vapor phase has been investigated by means of an olfactometer which permitted quantitative control of stimulus concentration. The median rejection threshold was selected as a criterion of response. As was true in the case of contact chemoreception, the distribution of thresholds in the fly population is normal with res...
متن کاملOlfactory detectability of homologous n-alkylbenzenes as reflected by concentration-detection functions in humans.
As part of our systematic exploration of chemical determinants for the olfactory potency of vapors towards humans, we measured concentration-detection functions for the odor of the homologous n-alkylbenzenes toluene, ethylbenzene, butylbenzene, hexylbenzene, and octylbenzene. A vapor delivery device based on dynamic olfactometry and calibrated by gas chromatography, served to test groups of 16 ...
متن کاملOlfactory psychometric functions for homologous 2-ketones.
We measured concentration-detection (i.e., psychometric) odor functions for the homologous ketones propanone (acetone), 2-pentanone, 2-heptanone, and 2-nonanone. Under a forced-choice procedure, stimuli were presented via an 8-channel air-dilution olfactometer that allowed natural sampling of the odorant and whose output was quantified by gas chromatography. Subjects (17-22 per compound) compri...
متن کاملOlfactory Stimulation of Blowflies by Homologous Alcohols* By. v. G. Dethier A~d M. T. Yost
Although the study of olfaction has enjoyed as old and honorable a history as that of vision and hearing, it is painfully apparent that our understanding of this branch of physiology is little more advanced today than it was at its inception (of. Crozier, 1934; Geldard, 1950; Symposium on Olfaction, 1950; Pfaffmann, 1951 a, 1951 b). The foremost obstacle to research has been an inability to qua...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Pharmacology Biochemistry and Behavior
سال: 2008
ISSN: 0091-3057
DOI: 10.1016/j.pbb.2007.12.023